Clinical Trials

Alabama Oncology considers clinical research to be an important part of our overall mission. We’re proud to provide access to cutting edge treatment options in your community, close to home.

If you think you might be interested in taking part in a clinical trial and would like to speak to someone for more information, please ask your physician or contact a clinical research coordinator at (205) 803-4389.

Alabama Oncology participates in a broad list of innovative studies that strive to advance medical science. Please see the current list of studies we have available for our patients below:
 

Breast

 
Pfizer A5481082 Palbociclib in Hormone Receptor Positive Advanced Breast Cancer: A Prospective Multicenter Non-Interventional Study

https://clinicaltrials.gov/ct2/show/NCT03280303?term=A5481082&rank=1

AstraZeneca D5336C00001 A Phase II, Open Label, Randomised, Multi-centre Study to Assess the Safety and Efficacy of Agents Targeting DNA Damage Repair in Combination With Olaparib Versus Olaparib Monotherapy in the Treatment of Metastatic Triple Negative Breast Cancer Patients Stratified by Alterations in Homologous Recombinant Repair (HRR)-Related Genes (Including BRCA1/2) (VIOLETTE)

https://clinicaltrials.gov/ct2/show/NCT03330847?term=nct03330847&rank=1
 

Lung

 
Bristol-Myers Squibb CA209-384 Checkmate 384 A Dose Frequency Optimization, Phase IIIB/IV Trial of Nivolumab 240 mg Every 2 Weeks vs Nivolumab 480 mg Every 4 Weeks in Subjects With Advanced or Metastatic Non-small Cell Lung Cancer Who Received up to 12 Months of Nivolumab at 3 mg/kg or 240 mg Every 2 Weeks

https://clinicaltrials.gov/ct2/show/NCT02713867?term=nct02713867&rank=1

Bristol-Myers Squibb CA209-817 A Phase Illb/IV Safety and Efficacy Trial of Flat Dose Nivolumab In Combination With Ipilimumab in Participants With Non-Small Cell Lung Cancer

https://clinicaltrials.gov/ct2/show/NCT02869789?term=nct02869789&rank=1

Bristol-Myers Squibb CA209-907 An Open-label, Single-arm Phase II Safety Study of Nivolumab in Participants With Advanced or Metastatic Non-small Cell Lung Cancer Who Have Progressed During or After Receiving at Least One Prior Systemic Regimen (CheckMate 907: CHECKpoint Pathway and nivoluMAb Clinical Trial Evaluation 907)

https://clinicaltrials.gov/ct2/show/NCT03090737?term=nct03090737&rank=1

AstraZeneca D419QC00001 A Phase III, Randomized, Multicenter,Open-Label, Comparative Study to Determine the Efficacy of Durvalumab or Durvalumab and Tremelimumab in Combination With Platinum-Based Chemotherapy for the First-Line Treatment in Patients With Extensive Disease Small-Cell Lung Cancer (SCLC) (CASPIAN)

https://clinicaltrials.gov/ct2/show/NCT03043872?term=nct03043872&rank=1

PharmMar PM1183-C-003-14 Phase III Randomized Clinical Trial of Lurbinectedin (PM01183)/Doxorubicin (DOX) Versus Cyclophosphamide (CTX), Doxorubicin (DOX) and Vincristine (VCR) (CAV) or Topotecan as Treatment in Patients With Small-Cell Lung Cancer (SCLC) Who Failed One Prior Platinum-containing Line (ATLANTIS Trial)

https://clinicaltrials.gov/ct2/show/NCT02566993?term=nct02566993&rank=1
 

Lymphoma

 
Debiopharm International SA Debio1562-201 A Phase 2 Study to Evaluate the Efficacy and Tolerability of Debio 1562 in Combination With Rituximab in Patients With Relapsed and/or Refractory Diffuse Large B-Cell Lymphoma and Other Forms of Non-Hodgkin’s Lymphoma

https://clinicaltrials.gov/ct2/show/NCT02564744?term=nct02564744&rank=1

TG Therapeutics UTX-TGR-205 A Phase 2b Randomized Study to Assess the Efficacy and Safety of the Combination of Ublituximab + TGR-1202 With or Without Bendamustine and TGR-1202 Alone in Patients With Previously Treated Non-Hodgkin’s Lymphoma

https://clinicaltrials.gov/ct2/show/NCT02793583?term=nct02793583&rank=1
 

Multiple Myeloma

 
Bristol-Myers Squibb CA204-008 Prospective Research Assessment in Multiple Myeloma: An Observational Evaluation (PREAMBLE)

https://clinicaltrials.gov/ct2/show/NCT01838512?term=nct01838512&rank=1
 

Myelofibrosis

 
Incyte INCB50465-201 A Phase 2 Study of the Safety, Tolerability, and Efficacy of INCB050465 in Combination With Ruxolitinib in Subjects With Myelofibrosis

https://clinicaltrials.gov/ct2/show/NCT02718300?term=nct02718300&rank=1
 

Renal

 
Bristol-Myers Squibb CA209-914 A Phase 3 Randomized Study Comparing Nivolumab and Ipilimumab Combination vs Placebo in Participants With Localized Renal Cell Carcinoma Who Underwent Radical or Partial Nephrectomy and Who Are at High Risk of Relapse

https://clinicaltrials.gov/ct2/show/NCT03138512?term=NCT03138512&rank=1
 

Sickle Cell

 
Global Blood Therapeutics GBT440-031 A Phase 3, Double-blind, Randomized, Placebo-controlled, Multicenter Study of GBT440 Administered Orally to Patients With Sickle Cell Disease

https://clinicaltrials.gov/ct2/show/NCT03036813?term=nct03036813&rank=1